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Sensitivity to cobalt and/or Vitamin B12 is a contraindication Clients with chronic liver and/or kidney dysfunction, Lebars disease (hereditary eye disease) or abnormal red blood cells (megaloblastic anaemia) should not take frequent B12 injections

This typically depends on factors like the depth of each scar, how many are present, and more

Compounded medications are not reviewed or approved by the FDA for safety or effectiveness in the same manner as commercially available drugs

Additionally, the deep red colour of the drug may cause chromaturia, interference with some colorimetric laboratory tests, and pigmentation of hemodialysis ultrafiltrate, which may cause an erroneous blood leak detection alarm on some hemodialysis machines [15, 19]