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Astrocytes, through the ANLS, are pivotal in sustaining the normal physiological functioning of neurons [15]
692 HO-1 is a regulator of iron and ROS homeostasis
Moreover, it was found that the combination of FA (40 mg/mL) and genistein (27 mg/mL) in the treatment of Ab31-35-exposed rat cortical neuron cultures showed an enhanced neuroprotective effect by down-regulating the apoptotic-related genes Bax, p53, and caspase3 and up-regulating Bcl-2 [126]
It acts as an anti-inflammatory agent, functions as an antioxidant, stabilizes cell membranes, and induces MT [182]
