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Insulin Resistance, Affective Disorders, and Alzheimers Disease: Review and Hypothesis

Its important to note that while there are similarities between Phase I and Phase II metabolism, there are also distinct differences in the types of reactions, enzymes involved, and the nature of the metabolites formed

Pregnant or breastfeeding women , since research regarding safety in such cases is limited

Meakin, P.J., et al., Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance