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Intracellular Hormone Receptors (Nuclear Receptors) The steroid/thyroid hormone receptor superfamily, which includes but is not limited to, the glucocorticoid (GR), vitamin D (VDR), retinoic acid (RAR) and thyroid hormone (TR) receptors, is a class of proteins that reside in the cytoplasm, or the nucleus, and bind their lipophilic hormone ligands in these locations since the hormones are capable of freely penetrating the hydrophobic plasma membrane

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6.3 Challenges in targeting lipid peroxidation for cancer therapy Lipid peroxidation varies significantly among different types of tumors, individuals, and even in response to various therapeutic strategies

The penile plaque was located ventrally and at the distal third of the penis