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Similarly, growth hormone (GH) may be related to ALS as one trial found that ALS patients had impaired GH secretion compared to healthy controls (Morselli 2006)

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Peroxisomes play particularly important roles in lipid metabolism, ether-phospholipid biosynthesis, and reactive oxygen species (ROS) metabolism 3

AP1 is a complex of several proteins including JUN, which is upregulated in motor neurons derived from SOD1 patients compared to other neurons, providing potential mechanistic insights into the selective degeneration of motor neurons in ALS (Bhinge et al., 2005)