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For example, the nanoparticle drug PAP-SeNPs constructed from SeNPs and red mushroom polysaccharide component (PAP-1a) can significantly activate the Tlr4/Myd88/NF-B pathway, polarizing M2 macrophages into M1 macrophages thereby activating anti-tumor immune responses (237)

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j , Uninfected M treated with KL1 (10 or 40 M) were assessed for viability (CellTiter-Fluor