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Role of the Nrf2/ARE pathway in the mtDNA reparation

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125127 When pyruvate kinase is deficient or dysfunctional, there is an increased reliance on alternative pathways for energy production leading to increased breakdown of ATP and subsequent accumulation of adenosine monophosphate

Since the embryological development is so complex and most of the time, the intricacies of biochemical and neurological development of the child necessitate that errors do occur