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Description
Its tri-methylamino group and carboxylic group enable interactions with the corresponding poles in membrane phospholipids, glycolipids, and proteins
Elevated levels of -hydroxybutyrate (-HB) bind to the NLRP3 inflammasome, inhibiting its activity and thereby reducing the release of the inflammatory factors IL-1 and IL-18, slowing myocardial fibrosis and promoting the recovery of the ejection fraction during heart failure progression ( However, acetoacetic acid (AcAc) is considered to have pro-inflammatory effects
Disposition of valproic acid in self-poisoned adults
Subramanian, SL
