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[40]O.B

In these conditions, NO starts to compete with SOD, removing superoxide anion (O 2 ) and causing the formation of peroxynitrite (Table 1) [37]

While curcumin supplementation in dogs appears to significantly reduce the expression of genes associated with inflammation, 53 its overall effect on pain and mobility in dogs with osteoarthritis has produced variable results, exhibiting improvements in subjective pain assessments in some cases of dogs with osteoarthritis, but not exhibiting reliable objective improvements in mobility

However, some findings have inherent limitations due to tight sample size, uneven gender distribution, and lack of control groups