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Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A carboxylase expression and even prevents the reduction of carnitine and palmitoyltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of obese rats

However, high expression of SLC7A5 in tumor cells predicts reduced expression of immune-related genes, reduced immune cell infiltration, and poor efficacy of immunotherapy

Therefore, the addition of FAO inhibitors to conventional antitumor drug regimens can improve therapeutic efficacy and reverse cancer drug resistance, which has great potential in tumor therapy [179]

Short review of two cases