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In a similar study, the pivotal role for the IGF-1 in insulin sensitivity has received further support from liver-specific IGF-1 KO mice which exhibited overt insulin resistance and hyperinsulinaemia that was reversed by the administration of IGF-1 [161]

The cognitive functions were evaluated using the novel object recognition test (NOR) and the passive avoidance test (PAT)

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We then prescribe a series of physical exercise and therapies to target those brain regions for recovery
