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Its FDA-approved for reducing visceral adipose tissue, particularly in HIV-associated lipodystrophy, but its effects translate well for general fat loss in the abdominal region

Treatment of diet-induced obese mice systemically with a potent NNMT inhibitor significantly reduced body weight and white adipose mass, decreased adipocyte size, and lowered plasma total cholesterol levels

doi: 10.1021/acs.jmedchem.9b00206

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