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L-Methylfolate is the only form of folate that crosses the blood-brain barrier 22 and can be used instantly in the body

Volkova A, Shadrina M, Kolomin T, et al (2016) Selank administration affects the expression of some genes involved in GABAergic neurotransmission

10.1124/dmd.114.062034 Drug Metab

Ferrari R, Guardigli G, Mele D, Percoco GF, Ceconi C, Curello S
