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4 Transaminase Upregulation and Targeting Amino Acid Synthesis for Cancer Therapy Another means of inhibiting glutaminolysis is to target alanine transaminase through L-cycloserine or aspartate transaminase through the inhibitor amino oxyacetate, which could almost completely halt the growth of breast cancer in xenograft mice [117, 118]
Recent research shows that EGCG treatment suppressed arsenic-induced oxidative stress by decreasing ROS generation and MDA levels and increasing SOD and CAT activities in the mouse thymus and spleen [110]
The 60-day minimum is risk mitigation in the absence of human pregnancy pharmacokinetics, not a guarantee of complete biological clearance of all downstream effects.
NAC also demonstrates immunomodulatory activity
