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PMID 10373343

Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress

Cancer stem-like cells: metabolic architects of immune resistance Cancer stem-like cells (CSCs) are a rare but highly influential subpopulation within lung tumors that possess the hallmarks of stemnessnamely self-renewal, pluripotency, therapy resistance, and a unique ability to initiate metastasis

There are now increasing evidence that show dysregulation of GSH synthesis in multiple conditions, such as aging, diabetes, pulmonary and hepatic fibrosis, alcoholic and cholestatic liver injuries