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Furthermore, the NF-B activation is related to impairing the epithelial barrier function by TJ disassembly

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In this context, taurine appears to attenuate As2O3 mediated toxicity (249), possibly by reducing the expression levels of phosphorylated JNK kinases, thereby ruling out the possibility that hepatic cells follow the apoptotic route after taurine treatment in As2O3-administered rats (248)

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