glutathione cycle pdf system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis LC-MS analysis of key components
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Here, we evaluated the combined inhibition of the glutathione and thioredoxin antioxidant systems in preclinical models of pancreatic ductal adenocarcinoma, using buthionine sulfoximine (BSO) that targets glutathione synthesis, and auranofin that targets thioredoxin recycling
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