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Importantly, it remains unclear whether the in vitro reduction of cADPR levels produced by extracellular CD38 in the presence of therapeutic mAbs leads to reduced intracellular Ca 2+ mobilization and decreased signaling potential

It is worth noting that some experiments have revealed increased NNMT expression in body fluids, including blood, urine, and saliva (12, 13, 40)

Sourander, Andre, et al
