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The medication (morphine (16 mg/kg s.c.), the tested agents (gastric pentadecapeptide BPC 157 (10 pg, 10 ng and 10 g/kg i.p.), naloxone (10 mg/kg s.c.), haloperidol (1 mg/kg i.p.) or saline (5 ml/kg i.p.) was given accordingly at either 30 min, 20 min or 10 min before the first assessment (time "0"), and subsequently, the mice were assessed at 15, 30, 45, 60, 90, 120, 150 and 180 min intervals (time "+")
10.1177/1073858406298554 52 KuczenskiR.SegalD
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The use of magnetic resonance spectroscopy to observe changes in chemical composition of the brain over time is novel, and glutathione happens to be one of the few antioxidants you can detect with this approach, Jeannie Padowski, the studys senior investigator, said in a news release
