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In this review we briefly summarize the mechanisms of GSH synthesis and homeostasis, while we will focus on the strict connection between GSH levels and oxidative/nitrosative stress and on the downstream redox changes that modulate signaling pathways involved in viral infection and autophagy (ATG)

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Yoon K.H., Lee J.H., Kim J.W., Cho J.H., Choi Y.H., Ko S.H., Zimmet P., Son H.Y

However, the underlying mechanism of global genomic DNA hypomethylation in ESCC is still equivocal

This enzyme catalyzes the ratelimiting step in GSH synthesis and contains a catalytic and a modifier (GCLm) subunit