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6 However, it must be noted that patients with severe neurological deficits or critically low levels of vitamin B12 should be treated with parenteral therapy, to ensure rapid replenishment of body stores to prevent irreversible consequences

Clinical trial and PubMed searches found evidence only tangentially related to weight loss (GLP-1 Phase 3/4 trials show weight loss, but *with* documented dietary/lifestyle context, contradicting the 'without diet change' framing)
A 5mg/ml vial of semaglutide concentrates twice the medication into the same volume as a 2.5mg/ml vial