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Description
Evidence for systemic accumulation with daily dosing is limited

Healy 2012

A.Giraud-BilloudM.Genaro-MattosT

Induction of t-LTD was unaffected by postsynaptic loading of MK-801 but completely blocked by presynaptic MK-801, indicating that t-LTD requires presynaptic, but not postsynaptic NMDA receptors (Rodrguez-Moreno and Paulsen, 2008 )
