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When pretreating the cells with N -ethylmaleimide (NEM, 20 mM), a trapping reagent of thiol species, for 0.5 h, the signals from the cytoplasmic regions are decreased in both green and yellow channels (Figure 7DF)

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The epididymis, heart, lung, liver, brain, adipose tissue, mammary gland, and digestive system are among the several other organs in which GPx3 is also present in activated form

Biochimica et Biophysica Acta (BBA) Mol Basis Dis 1863(6):14221435 Juaristi I et al (2017) ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate