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Description
The accumulation of DSBs has been linked to Hereditary sensory and autonomic neuropathy type 1 [41, 66], with the observation that high dose L-serine supplementation lowers plasma DSB levels and alleviates neuronal symptoms in HSAN1 patients, whereas alanine increases DSB levels and worsens peripheral neuropathy [67]
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Research suggests that stimulation of melanocortin 4 receptors (MC4R) may reduce amyloid-beta accumulation, support synaptic activity, and improve markers linked to neuroprotection
