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Preclinical studies showed lipolytic and anti-lipogenic effects, but human trials failed to demonstrate significant weight-loss outcomes

Sulforaphane treatment also led to suppression of key colorectal cancer stem cell markers, such as CD44 and CD133 in HCT116 and SW480 spheroids, facilitated by the TAp63 /Lgr5/ -catenin pathway (Chen et al., 2020), suggesting that exposure to sulforaphane could lead to lowered cell proliferation activity

doi: 10.3389/fmicb.2021.611323 Summary Keywords polycystic ovary syndrome, resveratrol, mechanism, metabolism, treatment Citation Chang H, Shi B, Wang Y, Lu F, Guan M and Wu X (2025) Effect and mechanism of resveratrol against polycystic ovary syndrome: a review