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[PubMed] [Google Scholar] 42.Wolf E, et al

Food and Drug Administration (FDA) approved olaparib for treating advanced ovarian cancer in individuals with germline BRCA mutations (Yelamos et al., 2020)

High IGF-1 levels could compete for binding to the IGF-1R thus reversing the inhibitory effect of IGF-1R-targeted antibodies [84]

Taking a smaller, highly bioavailable dose is often a more effective strategy
