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Colorectal cancer, vitamin D and microbiota: a double-blind Phase II randomized trial (ColoViD) in colorectal cancer patients

10.1093/pcp/pcx180

[59] used 3 IH neuron models (hypoxia duration: 2, 5, 10 min) to determine the appropriate hypoxia time to study autophagy, their results indicated that the hypoxia phase (1.5%O 2 ) for 5 min and reoxygenation phase (21%O 2 ) for 10 min led to significant difference on the markers of apoptosis and autophagy

Studies have shown that obesity induces increased M1 macrophages (M1) polarization in mice, which may further promote iron deposition, according to in vitro studies (63)