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PLoS One 11 , e0161105 (2016)
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Tumour cells with this genotype display a high level of plasticity, with an ASCL1-high/NEUROD1-low phenotype at early-stage disease and a NEUROD1-high/ASCL1-low phenotype in invasive late-stage tumours [148] (Table 1)
standardized to curcumin 95% when specified) exerts its major effects on reducing inflammation, oxidative stress and mitochondrial dysfunction ( In addition, curcumin is able to inhibit lipid peroxidation ( in vitro in neuronal and glial models of oxidative stress, and in vivo in male Sprague-Dawley rats
