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Laferrre B, Abraham C, Russell CD, Bowers CY

& Chang, X

Nicotine affects the functional activity of ion transporters, including Na + , K + , 2Cl cotransporter and Na + , K + -ATPase on BECs and inhibits P-gp activity in the CNS (Paulson et al., 2006

Introducing a substance that alters dopamine and norepinephrine levels, such as MPH, might disrupt the maturation of the prefrontal cortex and have lasting behavioral consequences
