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Thus, it is not surprising to see the paradoxical effect of stimulant treatment, which causes oxidative stress (El-Tawil, Abou-Hadeed, El-Bab, & Shalaby, 2011

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8 HeFH is characterized by elevated LDL-C concentration from birth and, if untreated, leads to premature ASCVD that may begin as early as 20 to 25 years of age in men and 40 years of age in women

Administration of AC reduced oxidative stress shown by lower ROS and MDA levels, alongside increased SOD and catalase levels
