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Additionally, TGF- accelerates tumor progression by suppressing immune surveillance, promoting angiogenesis, and inducing EMT, with pathway activation consistently linked to poor prognosis in lung cancer patients (Miyazono et al., 2012

doi: 10.1080/15502783.2023.2224751 [DOI] [PMC free article] [PubMed] [Google Scholar] [327].Minich DM, Brown BI
In comparison with DFO, patients treated with DFP exhibit more pronounced improvement in cardiac T2* values (123), higher left ventricular ejection fraction (123, 124), stronger cardiac protective effects (125), and a higher 5-year survival rate without heart disease (122)

Furthermore, in a maize cultivar with symptomless SCMV-resistance, a proteomic analysis revealed a down-regulation of two different GSTs in later phases of virus infection, pointing to a role of GSTs in establishing virus resistance at the early stages of pathogenesis (Wu et al., 2013a,b)
