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Cancer cells have a high demand for NADPH to neutralize the radical oxidized species (ROS), which they produce in large quantities [59]
Further, overexpression of GGT in prostate cancer cells promotes proliferation in vivo [108,109,110]
Since the implications of GPX3 in cancer have been well documented and extensively reviewed [23,24], this issue is beyond the scope of this paper, and this paper will focus primarily on its roles outside of oncology
Marconi, G
