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knocking down ELAVL1 alone noticeably decreased proliferation, migration, and invasion, but combining ELAVL1 and GAC knockdown (which depleted both glutaminase isoforms) did provide a small further decrease in cell growth, migration and invasion compared to that with ELAVL1 knockdown alone
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Colony formation assays revealed that LPE18:1 treatment promoted cell proliferation, whereas CAPZA1 knockdown attenuated this effect (Fig
A unique feature of oxaliplatin is its rapid non-enzymatic transformation to the reactive dichloro 1,2-diaminocyclohexyl-platinum complex and oxalate which occurs via replacement of the oxalate moiety with chloride ions in the blood plasma
