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The American Society for Parenteral and Enteral Nutrition (ASPEN) and the American Academy of Nutrition and Dietetics (AND) jointly published consensus diagnostic criteria (the ASPEN/AND Consensus Statement, 2012, updated 2021) that define malnutrition by etiologic category and severity using observable clinical indicators including weight loss, energy intake, body composition, functional status, and inflammatory markers

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J Clin Immunol 19:1-11, 1999 Biet F, Locht C, Kremer L: Immunoregulatory functions of interleukin 18 and its role of defense against bacterial pathogens