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Description
Yes-associated protein (YAP) is selectively activated in metastatic lesions in LNs, which leads to increased transcription of genes in the FAO signaling pathway
In addition, the vaccine improved the physical activity of middle-aged mice (50 weeks old) and extended the median lifespan of ZMPSTE24 KO mouse (model of progeria), an extreme model of accelerated aging 62
Anyway, focus on the positives I guess
[PMC free article: PMC286692] [PubMed: 2465552] 247
