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For the optic nerve axotomy model, intraperitoneal injections of 50 mg/kg EGCG at 30 min before axotomy, and at Day 2 and 4 after axotomy were able to attenuate RGC loss by 12% in rat retina along with reducing the upregulation of neuronal nitric oxide synthase and Bax protein expression, and further enhancing ERK 1/2 and Akt activation after axotomy [111]

Biofilms are thought to be responsible for more than 80% of microbial diseases, such as: Otitis media, the most common acute ear infection in US children Bacterial endocarditis, infection of the inner surface of the heart and its valves Cystic fibrosis, a chronic disorder resulting in increased susceptibility to serious lung infections Legionnaires disease, an acute respiratory infection resulting from the aspiration of clumps of Legionnella biofilms detached from air and water heating/cooling and distribution systems Chronic wounds (wounds that do not heal within three months) Hospital-acquired infections, such as infections acquired from the surfaces of catheters, medical implants, wound dressing, or other medical devices How might a biofilm explain the persistence of Lyme

Our Swiss Medical researchers have harnessed this knowledge to develop an inhibitor that reduces the gene's activity, thus providing a groundbreaking solution for those seeking a lighter, more even skin tone

Ciprofloxacin and nitrofurantoin were used as positive controls