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[7] Use is also contraindicated in patients with arterial bleeding

Tirzepatide (Mounjaro for diabetes, Zepbound for weight loss) activates two receptors GLP-1 and GIP which is why it tends to produce somewhat stronger weight-loss results on average

Common side effects include: Injection site reactions pain, redness, or swelling at the injection site Mild diarrhoea or gastrointestinal upset usually transient Skin reactions itching or rash (uncommon) Hypokalaemia rare, occurring when severe megaloblastic anaemia is corrected rapidly Serious adverse effects are extremely rare but may include anaphylaxis in hypersensitive individuals
Tendons receive only about 10% of the blood supply that muscles do
