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Description
These high levels of malonyl-CoA inhibit carnitine palmitoyltransferase 1 (CPT-1), the enzyme required for the transport of fatty acyl-CoAs into the mitochondria where they are subject to oxidation for energy production

The dysfunction leads to high renal loss of carnitine and lower concentrations of carnitine in blood and tissues

A striking feature of Group VIA-2 phospholipase A 2 is its lack of specificity for the fatty acid present at the sn -2 position of phospholipids, the enzyme being able to hydrolyze practically any fatty acid

High-density lipoproteins
