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Drosophila spaghetti and doubletime link the circadian clock and light to caspases, apoptosis and tauopathy

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Network construction and analysis algorithms, such as weighted gene co-expression network analysis (WGCNA), are used to identify gene network modules and key genes, while Protein-protein Interaction (PPI) network analysis algorithms construct networks based on protein interaction information, and MCODE is used to identify dense subgraphs within networks

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It has also been shown that coronavirus infection can inhibit the activity of numerous karyopherin-dependent host transcription factors including the vitamin D receptor (VDR) and hypoxia-inducible factor 2 [HIF2]-Epas, p53 in human lung cells [109]

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