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That's where glutathione before drinking steps in: this essential antioxidant becomes depleted as it tackles the toxic byproducts of alcohol metabolismespecially acetaldehyde, the molecule responsible for those dreaded hangover symptoms

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These actions collectively improve overall mitochondrial function, including enhancing energy metabolism, increasing ATP production, and reducing oxidative stress levels

In this pathway, the cycle is not completed and the carbon skeleton of Glutamine, entering the TCA as -Ketoglutarate, escapes as Malate with production of ATP at substrate level in the reaction catalyzed by the Succinyl-CoA Synthetase