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10.1161/CIRCRESAHA.116.305372 [DOI] [PMC free article] [PubMed] [Google Scholar] 142.Ranek MJ, Bhuiyan MS, Wang X

M.KirchhofD.ManningE.JosephJ

Depurinating estrogen-DNA adducts, generators of cancer initiation: Their minimization leads to cancer prevention

In such a situation, the ablation of GPx4 has been demonstrated to render tumor cells more susceptible to ferroptosis-eliciting agents, suggesting that GPx4 may emerge as a promising target for the development of novel therapeutic interventions (181, 182)
