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Hepatic encephalopathy caused by hyperammonemia is a frequent and serious complication of cirrhosis and commonly determines its prognosis

Pediatr Nephrol 27:13811387

12, 17 This triggers the release and/or production of neurotoxic and proapoptotic compounds such as nitric oxide synthase (NOS)
Postiglione A, Soricelli A, Cicerano U, et al