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Description
Factors such as the severity of the deficiency, the body's rate of usage, and individual metabolic differences all play a role

But if a patient suffers from conditions that prevent him from absorbing the vitamin from his diet, a lifelong intake is commonly required for health
Methylcobalamin is the active, methylated form of B12 that directly participates in the methionine cycle as a methyl donor for homocysteine remethylation

PMID 22450609
