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To maintain consistently elevated L-arginine levels, smaller doses throughout the day are recommended for example, 3 g of L-arginine in the morning after waking and 3 g before going to bed

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doi:10.1002/ptr.1091

High fat diet induced atherosclerosis is accompanied with low colonic bacterial diversity and altered abundances that correlates with plaque size, plasma A-FABP and cholesterol: a pilot study of high fat diet and its intervention with Lactobacillus rhamnosus GG (LGG) or telmisartan in ApoE(/) mice