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El interior de la membrana de las mitocondrias es impermeable a los acetil-CoA por que deben unirse a la carnitina para que el acetil-carnitina resultante sea transportado a la matriz mitocondrial

Pivalate is a branched-chain fatty acid anion that is metabolized to form an acyl-CoA ester, which is transesterified to carnitine and subsequently excreted in the urine as pivaloyl carnitine

hasta en el 80% de los pacientes con mieloma que han recibido tratamiento durante ms de 6 meses5254

Both cysteinylglycine and oxidized cys-gly are indicators of the redox state, which can be influenced by androgen receptor signaling (Chettimada et al., 2018