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B Vitamins and the Brain: Mechanisms, Dose and Efficacy A Review

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Diabetic patients with conventional subcutaneous insulin therapy had lower IGF-1 levels than patients with continuous subcutaneous insulin infusion and intraportal insulin infusion [13]

We observed this finding using body temperatures assessed (1) at most once per day via self-collection using handheld thermometers, and (2) at most once per minute via an unobtrusive wearable sensor device (worn on the finger)
