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Abstract Over the past few years, consultation cases thought to represent melanoma in situ have been received that consisted of otherwise normal intradermal nevi with an abnormal but benign junctional proliferation of melanocytes that we have termed benign atypical junctional melanocytic hyperplasia

Melanotan-I is used in laboratory research to explore MC1R receptor activity, peptide-receptor binding affinity, and downstream signalling pathways involved in melanocortin-mediated pigmentation

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