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Myelin degradation may be the result of lipid peroxidation mediated by peroxides, but the role of these specific toxic factors in the pathogenesis of MS remains partially elusive [9]

Residual TFA from preparative HPLC mobile phases can be cytotoxic and is under-reported on research-grade COAs

Combined solutions follow similar storage requirements, typically remaining stable for 30-60 days when kept cold and protected from light

Methods Mice We obtained mice with Nestin-Cre recombinase fused to a mutated estrogen receptor ( Nestin-Cre ER ) in a C57BL/6 background, ROSA26-EYFP in C57BL/6 background, and Igf1r with loxP sites flanking exon 3 ( Igf1r fl/fl ) mice in a mixed C57Bl/6 129 background from the Jackson Laboratory