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These antioxidants play a vital role in mitigating the oxidative stress induced by the freezing-thawing process, improving sperm viability post-thaw, and reducing DNA fragmentation

10.1016/j.thromres.2010.04.006

Several strategies can be employed to enhance ASTs bioavailability (see Table 7), including novel delivery systems, such as lipid-based carriers, nano delivery with a sustained-release (SR) system, and targeted delivery systems, and structural modifications, such as esterification, isomer form selection, etc