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Description
Translational Psychiatry
Polyunsaturated fatty acid (PUFA) accumulation in renal tubular cells renders the kidney susceptible to ferroptosis induced by lipid hydroperoxides (133)
Experimental findings indicate that the compound may trigger cellular mechanisms that release fatty acids from fat stores without significantly altering insulin or IGF-1 levels
The next clinical questions are durability, real-world persistence, cost, lean-mass effects, and whether the additional weight loss translates into fewer cardiovascular, renal, hepatic, and mechanical complications
